Focusing on the issue of low synchronization accuracy and slow convergence speed caused by the process of time synchronization which is susceptible to disturbance and communication delay in Wireless Sensor Network (WSN), an improved time synchronization algorithm was proposed from control perspective. Firstly, the clock synchronization state model was established, then, through the thought of modern control theory, a centralized control strategy was introduced, and the time synchronization state model based on control strategy was established. The centralized control scheme was designed based on global clock status information, and optimal control was obtained under the condition of minimizing the performance index function and the optimal estimation of Kalman filtering. Comparison simulation were carried out on the proposed clock synchronization optimization algorithm and Timing-sync Protocol for Sensor Networks (TPSN). The results showed that, from the 6th step of the clock synchronization, the synchronization error of the former was gradually smaller than that of the latter;when achieving the same relative high synchronization precision performances, the former required steps is about twenty percent of the latter;the variance of synchronization error convergence of the former was two orders lower than that of the latter. The results prove that the proposed algorithm of time synchronization has higher synchronization accuracy, faster convergence speed and lower communication load than TPSN.